Big Questions About CBD

What Does CBD stand for?

CBD or Cannabidiol is the decarboxylated form of the raw phytocannabinoid: CBDa. The “a” in this case stands for acid. Some would call CBD or cannabidiol the activated form, though there has been some recent research that has shown that CBDa has activity against the spike protein in Sars-CoV-2 or COVID-19, among many other activities, so this term is clearly inaccurate. There are many other related cannabinoids found in the cannabis plant, the most famous among these is THC or tetrahydrocannabinol. Lately there has been growing interest in other hemp derived cannabinoids including CBG and CBN. Research is finding uses for these as well and they are being combined with CBD to produce an entourage effect along with the terpenes found in the hemp flowers. CBGa, like CBDa is the raw form of the cannabinoid and seems to have a similar effect on the spike protein of Sars-CoV-2, while CBN or cannabinol seems to be useful as a sleep aid.

What is CBD?

CBD or cannabidiol is a naturally occurring molecule in cannabis that’s classified as a phytocannabinoid and was discovered in 1940 by Roger Adams. CBD is just one of 113 known cannabinoids found in the plant and is known to have systemic effects in humans and other animals including cats and dogs.

Does CBD do anything?

CBD is no longer the new kid on the block, and many people have tried various forms of CBD. Many of these forms have been mislabeled, low in CBD, or are in some other way prevented from entering the bloodstream. As such, some people wonder, does CBD do anything? There has been extensive preliminary research into the effects of CBD and it has been found to probably have some very wide ranging effects including:

  • Anti-Epileptic
  • Anxiolytic
  • Antipsychotic
  • Neuroprotection
  • Spasticity
  • Chronic Pain
  • Cancer
  • Addiction

A survey also found that people are also using CBD for:

  • Anxiety
  • Stress
  • General Health and Wellbeing
  • To help improve sleep
  • Insomnia
  • Arthritis/Joint pain
  • Chronic pain
  • Depression
  • Post-workout for sore muscles
  • To increase focus and productivity
  • Skin conditions
  • Menstrual Pain
  • Fibromyalgia
  • To help reduce restless legs
  • PTSD
  • To counteract THC
  • ADHD
  • Asthma or Allergies
  • Endometriosis
  • Epilepsy
  • Nausea
  • Multiple sclerosis
  • Menopause symptoms
  • And many others

 

But maybe you’ve tried some forms of CBD and wondered what’s the big deal? Does CBD actually do anything? It seems like a bunch of hype. Many forms of CBD are not very bioavailable and so you won’t get much in your bloodstream and therefore may not get any noticeable affect. Unfortunately many of the products hawked today are not what they claim (up to 69%!!!). To that we say—go to the source. The hemp plant and it’s flowers are the ultimate source of nearly all CBD on the market, given this and the fact that inhalation of cannabinoids seems to have the most potent immediate effect, we encourage you to try hemp flower—even if you haven’t seen an effect with other CBD products—the effect of hemp flower is undeniable. Remember, our CBD hemp Flower is farm direct and 3rd party lab tested and we provide this certificate of analysis with each batch of flower sold, so you know what you’re getting. What Golden Eagle Farms sells is farm-direct, small batch hemp flower and other hemp derived, minimally processed products. We care about what goes into our products and wish you only the best.

 

How Does CBD work?

The exact mechanisms of action for CBD are not fully understood. We do know that it acts on cannabinoid (CB) receptors of the endocannabinoid system found in humans and probably all mammals including cats and dogs. These receptors are found throughout our nervous system and we make our own endocannabinoids that normally activate these receptors. Their activation in-turn regulates many physiological processes including pain, memory, mood and appetite. The CB1 receptors in the brain, when activated by CBD, seem to lead to pain reduction and decrease angst. While CB2 receptors contribute to changes in immune cells that lead to some of the anti-inflammatory processes. These receptors are only two of the more than 45 different molecules that CBD interacts with in the human body.

 

How long does CBD stay in your system?

Some experimentation suggests that the maximum concentration of CBD is roughly 1.5hrs following sublingual ingestion, while inhalation of smoked or vaped CBD is much faster and leads to a greater concentration in the bloodstream. The initial half life of CBD looks to be roughly 1-2hrs with the remainder saying in your system for 24-36 hrs.

 

How long does CBD last?

 

The noticeable effects of CBD last approximately 1-2 hrs after ingestion, but since it stays in your system for up to 36 -48 hrs, your body will likely benefit from CBD for much longer.

By asking this question you may also be wondering about the shelf-life of CBD. This is a bit difficult to know given the different scenarios under which the various CBD containing products are stored. If kept in a dark cool place, the shelf life of CBD is approximately 12-18mos.

 

Can you take CBD with Alcohol?

Ingesting alcohol with CBD can lead to increased risk of sedation

 

What foods should be avoided with CBD?

  • Grapefruit products
  • St. John’s Wort

 

Can CBD be taken with medications?

Please ask you doctor prior to taking a CBD containing product, especially if you are concurrently taking any medications. It is not a simple yes or no answer, since there are many medications that are metabolized by your liver at rates that will be affected to a greater or lesser degree by CBD and other cannabinoids. For reference CBD is known to change the rate of metabolic activity of 6 common liver enzymes: CYP1A2, CYP2B6, UGT1A9, UGT2B7, CYP2C8, and CYP2C9. These enzymes break down a plethora of medications ranging from antipsychotic medications to blood thinners, and the changes in the rates of these enzymes’ metabolic activity is not known, so be cautious! CBD is generally regarded as safe, but the last thing you want is to bleed out because you didn’t check with your doctor!

 

Does CBD make you sleepy?

The two most common side effects of CBD are sedation and somnolence. This doesn’t mean that all forms and formulations containing CBD will make you tired, but grogginess is certainly a possibility and if that’s what you’re looking for, great! We have some High CBD strains that may just do the trick. It’s not just CBD that causes sleepiness or another way to say it is, the somnolence caused by CBD can be enhanced by other constituents of full spectrum hemp, the most potent of which is Myrcene (some of our strains are extremely high in this terpene). Not all CBD will make you tired though and some of our strains seem to be good for relaxing and focusing like Cherry Wine, Wife, and Suver Haze.

 

How does CBD for Sleep work?

 

Some preliminary research in rats has demonstrated a positive effect of CBD on improving REM sleep, in that when anxiety is at the heart of the REM sleep disturbance, CBD seemed to help. Insomnia is a common problem and can come in many forms from sleep initiation, to sleep interruption, non-restful states and sleep apnea. For this reason, CBD may not help in all cases and it is important to talk with your doctor to determine if CBD can help with insomnia in your case. Many of our customers claim that our hemp helps them sleep and have written about this in their reviews.

 

Can you OD on CBD?

Up to 1500mg/day are safely tolerated and this CBD dose can be taken daily while being well tolerated. The amount needed to become toxic is 20,000mg in a single day. This would take a big effort. CBD is generally regarded as safe without risk of overdose or dependency, but that doesn’t mean you should test the limits. There are other side effects and unknown risks of high dose CBD, so it’s probably better to stick with reasonable doses in the 10-100mg range.

 

What does CBD feel like?

The best answers to this can be found in our reviews, where our customers share their first-hand experience and sometimes give very in-depth explanations. Overall people usually describe a sense of relief, whether that’s from the stress or anxiety of the day, or the musculoskeletal aches and pains resulting from arthritis, old injuries, and the like. The deep relaxation that follows is dose dependent and can lead to a state of sleepiness near bedtime for many folks, most of whom report a good nights rest following CBD. What we’ve noticed is that CBD hemp Flower tends to bring on these effects faster with a lower dose and has an undeniable nearly immediate effect (within 3-7mins), to the point of a body buzz, like being immersed in a hot spring or mud bath but without all the mess.

 

Does CBD get you high?

Never. Nada. Zilch. CBD will not get you high no matter how much you take (see can you OD on CBD?) So why does CBD make me feel high? Your body may experience a profound sense of relief that it may not have felt in years or even decades. This is a big change, and can feel like a “high,” but make no mistake, this is not the same stoney, can’t-whip-your-brain-into-action-staring-at-the-daisies experience associated with THC. It’s a body buzz only. Your mind will more than likely be clear and relaxed and if there’s a task to get done, you can still focus, and get to it.

While straight CBD will not get you high, not all hemp derived products are free from THC. The 2018 Farm bill stipulated that they contain less than 0.3% THC, so there may still be some THC in that full spectrum product you are interested in. So to get 10mg of THC you would need to take 3.3g of a Full spectrum hemp product containing 0.3%THC. In the case of our CBD hemp Flower, it would be something like 3.5g or a whole 1/8th!!! So if you’ve taken this much full spectrum hemp at once, you very well may have gotten high. We don’t recommend it. Stick to reasonable amounts.

 

Does CBD show up on a drug test?

 

Unfortunately we have had customers test positive on a 10-panel drug screening test. This is not always the case though, and it’s hard to know if our products were the only ones being taken. Drug screening tests vary widely on their sensitivity and specificity for THC, so don’t count on them to confuse CBD for THC, but some do give false positives. While a false positive drug screen test due to CBD is not the norm, we cannot guarantee that you will pass, so if you’re in doubt and passing the screening test is critical for you, please consider other natural options for finding relief. On the other hand, CBD causing a false positive is a known phenomenon and that alone may be enough to sway the test giver into running another drug screen to rule out CBD causing a false positive if you present them with this study. Full disclosure to the test administrator of all substances being consumed, prior to testing, is the first step to having a “screening” test not end up an “unemployment” test.

 

Does CBD make your Eyes Red?

No, CBD does not cause red-eyes. This classic tell-tale sign of a stoner is an effect commonly seen in THC consumers not found when CBD is consumed. The reason comes down to the type of receptor that THC binds (CB1) found in the eye and causing vasodilation of the tiny blood vessels in the eye, leading to the classic “red-eye” phenomenon seen in marijuana smokers. CBD does not bind to the CB1 receptor in the same way and therefore will not cause your eyes to become bloodshot red. Not to worry with CBD, no one will mistake you for a stoner or ask you if you’ve been crying. CBD will not cause you eyes to turn red.

 

What does CBD do to the brain?

 

Preliminary research suggests that CBD exerts its effect on the endocannabinoid system directly and by changing the effects of native or endogenous cannabinoids. This generally results in anxiolytic, antidepressant, neuroprotective, anti-inflammatory, and immune system effects in brain chemistry. There may also be effects that are associated with improved neuroprotection and decreased inflammation following a brain trauma, as well as induce mechanisims that may have an effect in Alzheimer’s disease, Parkinson’s, Multiple sclerosis and Huntington’s disease.

 

 

Cannabidiol Adverse Effects and Toxicity

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052834/

 

An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/

 

Safety and side effects of cannabidiol, a Cannabis sativa constituent

https://pubmed.ncbi.nlm.nih.gov/22129319/

 

Full-Spectrum CBD May Trigger Positive THC Result

https://www.questdrugmonitoring.com/blog/2021/full-spectrum-cbd-may-trigger-positive-thc-result#:~:text=Use%20of%20so%2Dcalled%20%E2%80%9Cfull,study%20published%20in%20JAMA%20Psychiatry.

 

Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats

https://pubmed.ncbi.nlm.nih.gov/21867717/

 

Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems

https://jcannabisresearch.biomedcentral.com/articles/10.1186/s42238-021-00061-5#Fig1

 

 

Medical Fraud, Mislabeling, Contamination: All Common in CBD Products

 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723146/